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Path: ISSHA » Welcome to ISSHA » Harmful Algae Links » Phycotoxins » Okadaic acid, DTX (DSP)

Diarrhetic Shellfish Poisoning and Organisms

New additions are indicated by an asterisk (*). Last update: 29 November 2010.

Kindly send suggestions of HAB links you would like us to add, corrections for broken links, or corrections to the text that describes the link, to Karin Rengefors (ISSHA's Secretary).

 

Diarrhetic Shellfish Poisoning: Harmful Algae Website; Woods Hole Oceanographic Institution, Woods Hole, MA, USA

Neurotoxins from Marine Dinoflagellates: A Brief Review: by D.-Z. Wang (2008) Mar. Drugs 6: 349-371; Open Access PDF file (521 KB); discusses DSP

Diarrhetic Shellfish Poisoning: Information from Lora E. Fleming, NIEHS Marine and Freshwater Biomedical Sciences Center, Oceans and Human Health Center at the University of Miami Rosenstiel School, FL, USA

Diarrhetic Shellfish Poison: NOAA, Northwest Science Fisheries Center, Seattle, WA, USA

Diarrheic Shellfish Poisoning: Marine & Freshwater Biomedical Science Center; Oceans and Human Health Center at the University of Miami Rosenstiel School, Miami, FL, USA

DSP: University of Miami NIEHS Marine and Freshwater Biomedical Sciences Center

Dinophysis spp PCR detection Kit: DIATHEVA, Fano, Italy

Harmful algal blooms species in thin layers (HABIT): EU project to study Dinophysis in thin layers; pdf file of poster on the project; National University of Ireland, Galway, University Road, Galway, Ireland

Description of DSP Toxins: FAO Food and Nutrition Papers. Note: this section includes pectenotoxins and yessotoxins, but these are incorrectly grouped with the DSP toxins; also, the structure of DTX2 is incorrect (it was revised in 2007; see the Larsen et al. 2007 paper, below: DOI 10.1021/tx700016m)

Larsen, K., D. Petersen, A.L. Wilkins, I.A. Samdal, M. Sandvik, T. Rundberget, D. Goldstone, V. Arcus, P. Hovgaard, F. Rise, N. Rehmann, P. Hess, and C.O. Miles. 2007. Clarification of the C-35 stereochemistries of dinophysistoxin-1 and dinophysistoxin-2 and is consequences for binding to protein phosphatase. Chem. Res. Toxicol. 20: 868-875. (Publisher's abstract)

Binding of DSP toxins to Protein Phosphatase: QuickTime movie of how OA, DTX1 and DTX2 bind to PP2A. Link to above paper in Chem. Res. Toxicol., 2007, 20: 868–875, DOI 10.1021/tx700016m

Huhn, J., P.D. Jeffrey, K. Larsen, T. Rundberget, F. Rise, N.R. Cox, V. Arcus, Y. Shi, and C.O. Miles. 2009. A structural basis for the reduced toxicity of dinophysistoxin-2. Chem. Res. Toxicol. 22: 1782-1786. (Publisher's abstract)

EFSA advice on the Okadaic Acid and Analogues: European Food Safety Authority. PDF files of the Summary and of the Opinion

DSP Toxin Certified Reference Materials: National Research Council of Canada, Institute for Marine Biosciences, Certified Reference Materials Program, Halifax, NS, Canada. Available standards: CRM-DSP-Mus-b (okadaic acid plus DTX1 in a mussel extract), CRM-OA-c (okadaic acid)

* Okadaic Acid (DSP) ELISA Test Kit: Sold by Abraxis, Warminster, PA, USA

 

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News

Microarray Workshop

2012-01-31

EU FP7 MIDTAL (Microarrays for the Detection of Toxic Algae) workshop in Naples, Italy at the Stazione Zoologica Anton Dohrn from April 16-17, 2012 in the use of microarrays for the detection of toxic algae and the toxins they produce. Application deadline February 15, 2012.

Lifetime achievement award to Paerl

2011-09-02

Hans Paerl, professor at the University of North Carolina at Chapel Hill’s Institute of Marine Sciences in Morehead City, USA, is the 2011 winner of the Odum Award for Lifetime Achievement.

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